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PCI is proud to announce the Spring 2018 Cohort for the Penn I-Corps Accelerator Program.
Chromosense is a minimally invasive procedure to determine whether an embryo has the correct number of chromosomes. We use carbon nanopipette technology, which can pierce and manipulate single cells without inflicting damage, to inject molecular beacons into the nuclei of developing embryo cells.
Our solar technology utilizes wide band gap semiconductors to capture more of the sun’s energy, including visible light. Our ultra thin cell is optimized as a topping layer to conventional silicon solar cells, taking advantage of manufacturing economies of scale. Combined cell efficiency with our layer is 75% performance improvement over silicon cells alone.
EnvoyatHome has developed a system which uses non-invasive (passive) activity monitoring. Alerts can be set up for both normal movement patterns and exceptions/deviations to patters.
We developed an occupancy sensor that snaps onto toggle light switches, providing instant automation and energy savings without the need to rewire or replace the light switch itself.
Perform rapid DNA testing in batch using nanopores technology developped at Penn.
Applying carbon nano pipetes in a completely novel manner to transfect cells to treat Epidermolysis Bullosa (EB), a group of rare genetic skin conditions, which is characterized by extremely fragile skin and recurrent blister formation, resulting from minor mechanical friction or trauma.
There is currently no diagnostic for pre-symptomatic Pancreatic cancer; by the time symptoms are present the disease is generally fatal. We are developping a diagnostic based on biomarkers identified by the Zaret lab at the University of Pennsylvania.
Automatic Anatomy Recognition (AAR) is a body-wide and generalizable image segmentation and analytics methodology that can be used to automatically quantify organs and diseased tissues in MRI, CT & PET-CT scans. The technology can be deployed to help physicians plan treatment and assess response for patients with cancer and neurological disorders.
Hundreds of millions of dollars are lost annually due to fresh apple spoilage in the packing and distribution phase. Our biosensors measure ethylene gas, which reliably and efficiently measure fruit maturation using mechanisms of the fruits themselves.
Developing an enhanced care management/coordination Health IT tool called SwaddleTool to support treatment babies & mothers recovering from opioid addiction.
PCI is proud to announce the Fall 2017 Cohort for the Penn I-Corps Accelerator Program.
Researchers and biologists who need to visualize the entire structure of a biological specimen will use our add-on imaging device along with our tissue clearing system to overcome imaging limitations and to simplify and expedite workflow unlike the existing prohibitively expensive equipment.
Water Agency Managers who need to achieve sustainability and comply with new regulations will use our water exchange to reduce regulatory burden and to streamline the transfer of water unlike legacy water transfer operations.
Lung transplant teams who need to transplant lungs will use our Biomimetic Chest Cavity to limit damage to lungs ex-vivo and therefore increase the pool of available organs unlike traditional cold buffer storage and EVLP.
Research Investigators who need to test the efficacy of their bone-related drugs will use our bone-on-a-chip to reduce time, money, and effort in large animal models/clinical trials and to produce translatable data unlike small animal models.
General dentists who need assistance in diagnosing x-rays will use our cloud-based, HIPAA-compliant dental software to minimize the x-ray diagnosis error rate and to augment their expertise, unlike the slow process of getting a second dental treatment opinion.
Software platform to assist teachers and school administrators to support struggling students by assessing student risk dynamically, communicating student progress to stakeholders, and implementing school-wide behavioral rewards system.
Jet lag and social jet lag suffers, who need to improve their sleep, will use our Jet Lag Goggle providing dynamic lights to realign the circadian and to improve their sleep, unlike sleeping pills.
Mental healthcare providers who need to diagnose, monitor and document treatment progress for patients with depression will use Naanoscope, which is a package that monitors behavioral and physiological measures to improve prognosis and improves documentation by reducing subjectivity.
Neonur is a neurocognitive assessment tool, utilizing the late gestational developmental pattern of coordination of suck swallow and breath, to aid in the monitoring of the readiness to orally feed, and neural development. Neonur provides appropriate oral feeding guidance to NICU staff and feeding specialists for both infant and mother resulting in improved care preventing readmissions, decreased anxiety, and the potential for earlier discharge from the hospital, and the researcher a tool to better understand neurocognitive delays.
Charge nurses who develop nurse-patient assignments will use our software to reduce the time, stress, and complexity of current methods, and make assignments more data-driven and efficiently unlike current manual approaches.
Neurologists and Neurosurgeons specializing in Parkinson’s disease who need to treat their patients will use our bio-engineered neural pathway to slow the progression of the disease and to restore motor function unlike current available treatments such as DBS and other medical interventions.
Health departments who need real-time water quality reports will use our digital early warning system to eliminate exposure to water-borne pathogens and to increase rapid and accurate diagnoses unlike day-long lab methods.
Special Thanks to our Instructors for the Fall 2017 course
PCI is proud to announce the Spring 2017 Cohort for the Penn I-Corps Accelerator Program.
The primary objective of this application is to perform proof-of-concept study for a novel, molecular-targeted radiotherapy for patients with metastatic melanoma. The proposed study will perform per-clinical characterization of a novel radio-iodinated form of L-DOPA. Based on perviously conducted preliminary studies, we expected to selectively delivery radio-iodinated L-DOPA directly to the tumor, thus providing improved anti-tumor activity in primary and metastatic melanoma lesions.
The Respi-Bed is an innovation that updates and consolidates existing technology already available with the ability to be used on every hospital bed. The design allows us to incorporate multiple monitoring and support systems onto a hospital bed, simply using the space currently taken up by the headboard
low cost, modular, scalable, compact, and light weight and intravenous infusion device with a full color, intuitive and easy to program wireless touch interface with an integrated camera scanner to scan bar code and QR codes with an additional and monitoring capabilities to support auto programming.
Our technology is an artificial protein that can bind and release oxygen under physiological conditions. It holds promise as a blood substitute for trauma patients when blood is not available for transfusion. Since the protein is simple, stable and well understood, its properties can be modified to increase efficacy and reduce toxicity. This type of redesign is often not possible in natural proteins. Additionally, our protein can be quickly and cheaply produced in quantity from bacteria.
Our product is the “bone-on-a-chip,” which is a small, patients-specific device that emulates bone microarchitecture and function in vitro. It will contain a porous bone structure with real bone that is generated from high-resolution MRI images (MRI to 3D rendering to 3D printing). Thus, the device will allow the user to perform pre-clinical trials of drugs, providing a non-invasive alternative to methods such as animal testing.
Current distractor systems used for expanding bones in the face/skull have an external component that protrudes through the skin to allow for activation of the device with a screwdriver; this is both a source of infection and social isolation. Our technology eliminates this problematic component, with activation instead being achieved wirelessly, through a magnetic mechanism. Importantly, this technology allows for a novel device that is fully buried under tissue.
Doctigo is a mobile recruitment app for moonlighting doctors, improving the way hospitals fill vacant shifts. Doctors build a profile, browse shifts and pick up extra work with less hassle. Doctigo unlocks maximal utility from the internal hospital workforce and reduces the need for expensive temporary staff via recruitment agencies. Doctigo is a finalist in AppItUP 2017, with a prototype app nearing completion.
For micro-entrerpreneurs and super individuals who want to make an impact by doing what they love, Floureer is a user-centered professional social platform that empowers users with democratized coaching and emotion-triggered profiles that attract resources and opportunities. Unlike other job marketplaces, Floureer empowers users to create a flourishing career rather than just “finding jobs or people.” In addition, Floureer provides all-free resources for laid-off population as its social impact.
Parents Input children’s voice using speech recognition system and Google API, and checklist of children’s behaviors. Then, the algorithms behind the app refers online pre-installed database children’s development research and assessment (for example, Child Behavior Checklist critique, Dynamic Indicator of Basic Early Literacy and Kids Integrated Data System by GSE). We also aim to collaborate with Dr. Michelle Johnson PM&R who invented Smart Toy Gym to expand the data collection and accuracy.
NanoSink utilizes metal sheets (developed by the Singh Center) with macroscopic surface area and nanoscale thickness as a replacement for common heatsink components, such as vertical fins. Using photolithography and atomic layer deposition (ALD), we can create a corrugated pattern which gives the plates structural integrity where otherwise they would be as flimsy as cellophane. Our models show order of magnitude improvement in heat removal while being smaller and requiring less powerful fans.
VisiPlate is a nanoscale drainage implant for open angle glaucoma patients. It consists of an ultrathin alumina plate attached to a small silicone drainage tube and is surgically implanted in the eye. The ultrathin (25-100 nm) plates have a honeycomb corrugation that provides rigidity, allowing for easy manipulation by hand and exceptional strength. By draining fluid from the eye to a space above the plate, VisiPlate lowers intraocular pressure and prevents blindness. Y-Prize 2017 winner (https://yprize.upenn.edu)
PCI is proud to announce the Fall 2016 Cohort for the Penn I-Corps Accelerator Program.
Air-gun based technology to research traumatic brain injury (TBI) at the cellular level
The device is composed of a patented air-gun based technology that can vary pressure frequencies to study a wide range of cellular injury and response, and an imaging component that allows for real-time observation. Initially intended as a research tool to study cellular injury due to traumatic brain injury (TBI).
Fully automated and closed system for T-cells for adoptive cell therapy.
Fully automated and closed system for manufacturing genetically-modified T cells for adoptive cell therapy.
Kayak for online groceries, a price comparison tool
DURCHBLICK is a price comparison tool for online groceries, that allows users to save up to 30% on every purchase by comparing the price of their individual, full basket across all online grocery retailers. Through our ‘shopping list tool’ we further enable users to do their weekly shopping in less than 15 minutes.
Connecting schools with where they want to go
An integrated education platform that connects organizations with wellness solutions and passionate practitioners.
Modular low cost multifunctional tool for cataract surgery.
Safe and effective meniscus tear treatment
Current instruments and techniques often cannot treat meniscus tears optimally. We are developing methods and devices that will make meniscus tear treatment safer and more effective. These innovations are protectable intellectual property. Ultimately, we plan to manufacturer or license this technology.
Stay connected to the people that matter most.
inTouch is a mobile application that keeps non-sales professionals connected to the people that matter most. It is a works by streamlining their personal and professional contacts across different social mediums (ie. texts, emails, FB, Linkedin), intelligently reminding them to keep in touch, and allowing them to reach out with just a few clicks (using pre-made drafts and calendar integration).
Deliver drugs when needed using mechanical signals
A mechanically-activated drug delivery platform to deliver therapeutics in response to physical activity to augment repair of orthopaedic tissues using novel microcapsule technology.
Bridging the gap between the physical and virtual worlds
Merge utilizes novel 3D mapping and virtual reality technologies to allow consumers to visualize and manipulate real objects in the virtual world.
Biometric data to improve the assessment and treatment of mental health illnesses
NeuroFlow’s software platform quantifies stress using electroencephalogram (EEG) data, allowing physicians to measure a patient’s mental health over time and in response to various treatments. This software is used in combination with plug-and-play wireless EEG headsets that allow for minimal interruption of doctors’ and therapists’ current workflow and time constraints.
Smart robotic pet companion to reduce social isolation among the elderly population
We help increase trust in data science by autiomatically reproducing and logging analyses.
Ninety percent of scientists acknowledge a reproducibility crisis, they cannot replicate previously published works. Computational research and Data Science in particular should be reproducible because these analyses can be scripted. RaaS is a cloud based assistant that follows data scientists, replicating and logging everything they do. This ensures others can trust and replicate computational workflows.
Dignified rapid-drying composting toilets for high density settlements
revoLOOtion aims to solve the sanitation crisis starting with ⅔ of the world who doesn’t have access to private toilets. We provide dignified, delightful-to-use, odorless, rapid-drying composting toilets to urban families in high density informal settlements who have had to rely on unhygienic shared toilets or no toilets at all (read: open defecation).
At-home blood count testing for chemotherapy patients
Sanguis is a blood cell count monitoring device that patients can use at home to track their health.
PCI is proud to announce the 2016 Cohort for the Penn I-Corps Accelerator Program.
The first fintech startup empowering Black male millennial to pool and invest their money while building their community – together.
Sitting at the intersection of fintech, financial education, and a lifestyle membership club; Breaux Capital is the first financial services startup for Black Male Millennials. Inspired by organizations that empower women to build wealth & culture, Breaux Capital empowers Black millennials, with a focus on Black males, to leverage the power of pooling capital resources for wealth creation. We provide a platform for members to: gain investment and entrepreneurial knowledge, equitably invest their money, network, and serve their community as a cohesive group via our products BreauxEDU and BreauxBOX as well as our membership club the Breaux100.
Novel robotic technology delivers affordable, accessible, and effective rehabilitation to all regardless of where they live in the USA and the world
Developing a vest that severe COPD patients wear to offload their work of breathing and alleviate their shortness of breath.
Severe COPD (chronic obstructive pulmonary disease), popularly called emphysema, is a smoking-related lung disease that causes 2 million Americans to suffer years of intolerable shortness of breath. RightAir’s AIR-AD, is a respiratory assist device that fits like a vest over the chest and offloads the work of breathing. With each breath in, the AIR-AD generates a vacuum that helps lift the chest and abdomen, drawing air in. With each breath out, the AIR-AD increases pressure over the chest and helps the patient breath out faster. By assisting the work of breathing, patients no longer feel short of breath and can once again engage in normal daily activities.
Building low-cost, seamlessly implementable, and environmentally friendly green technologies
Root, is an outlet attachment that controls, monitors, and optimizes electricity usage. It uses a data driven approach with regards to the users Bluetooth and Wi-Fi signals in order to make decisions about energy waste. For example, if a user leaves home and leaves appliances on, he gets notifications asking if they should be turned off.
PCI is proud to announce the 2016 Cohort for the Penn I-Corps Accelerator Program.
Read the full press release here.
Technology for athletes that want actionable information on their physiological to optimize their training benefit and drive decisions about type and intensity of workout
Process to easily transport and deliver medicinal drugs to patients all across the world enables through a process that quickly and easily encapsulates and delivers drug
A sutureless magnetic device that allows for vessels (arteries, veins, etc.) to be put back together quickly, securely, and easily during cardiac and vascular surgery
Wearable augmented reality technology for management and execution of wet experimental protocol
Technology that serves as a peer-to-peer learning platform that provides use- generated content to teach technology to elders thereby improving their quality of life
Device that socially engages office workers in the same location or remotely. Its first version senses his environment and sends playful messages on Slack.
Device that connects bystander CPR-certified individuals with at-risk victims for cardiac arrest to reduce emergency response times, and improve patient outcomes
Technology that facilitates teams through a multi-faceted, matrix driven algorithm that pairs individuals based on needs, skills, start-up phase and personality traits
Robots functionalized to run microscale experiments including transporting and delivering drugs directly to cells and taking precise biological measurements
Technology that enables proprietary gold nanoparticles are taken into the tumor cells where they enhance radiotherapy and are then biodegraded and excreted from the body
Device that reduces counterfeit medication globally by using nano-markers providing peace of mind to patients and product protection to drug manufacturers
Our technology helps diagnose and differentiate types of shock to improve diagnosis and initiation of appropriate therapy
Device that is a high-performance motor driver to push motors past their present limits while increasing efficiency, lowering noise, reducing vibrations, heightening precision, and improving control
Technology that provides real time and reviewable metrics to athletes completing barbell based movements via equipment-based activity trackers
SonoSolve helps remove clogs and prevent biofilm formulation utilizing ultrasonification technology
Resources can be found here:
The Summer 2015 Penn I-Corps Site Cohort included:
A wearable device that enables patients to track their recovery from musculoskeletal injuries by monitoring the movement of their joints
A solution to Quantitative Radiology by localizing and delineating of all major organs in multiple body regions using MRI, CT and PET/CT images for applications in radiation therapy planning, medical oncology and surgical planning
A virtual community for change makers to connect, collaborate and turn their ideas into action
Developing a technology to rapidly and objectively diagnose concussions for medical, athletic and personal use
aims to make eyelash extensions more ubiquitous by designing tools that allow lash stylists to quickly and safely give consumers thick, long and beautiful lashes
LifeCycle improves patient outcomes while saving patients, municipalities and payers hundreds of millions of dollars. In non-emergency situations, LifeCycle reduces costly transports by leveraging the medical opinions of its on-scene paramedic and doctor connected via telemetry.
the easiest and most authentic way to travel to Latin America. Our platform, like AirBnb,helps travelers find unique adventures
aims to provide mothers an improved breastfeeding and pumping experience by integrating technology in a nursing bra to accelerate milk expression and provide relief from mastitis & engorgement
design and creates preventative mesh technologies and surgical devices for abdominal hernia
Develops a detector that more accurately determines the proton range for patients undergoing proton therapy treatment
offers an effective, low-cost, and mineral-based antimicrobial additive for medical device, household appliances, and public transportation hot spots
a mobile application that encourages honest communication among university students, and increases their awareness of the available on-campus resources
Fabrication of super-resolution microscope slides, improving the imaging resolution of a microscope
developing innovative solutions to promote independent living and aging-in-place for older adults by helping to improve their financial security