Penn Center for Innovation

CAR-M era begins as Carisma doses first patient

Posted on March 18, 2021 — Jessica Jones Gupta

Carisma Therapeutics, the University of Pennsylvania spinout, announced today that they had dosed their first patient with CAR-macrophages, or what they call CAR-M. Relying on a bubbly immune cell that eats pathogens and often gathers around solid tumors, they hope it can bring the benefits of cell therapy into places where CAR-T has consistently failed.

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