Penn inventors and researchers can choose to form startup companies leveraging their own expertise and partners or with direct support from Penn. PCI provides a number of programs that support startup formation through our PCI Ventures group, those resources can be found here.
Additionally, PCI works closely with Penn faculty to advise them on how to create a startup company as well as with new companies to license Penn technology.
Search our portfolio below, and click on each startup to learn more about their technologies, inventors, and whether they are looking for investors or new employees.
Advac Therapeutic
Development of vaccines and therapeutics for the treatment of infectious diseases and cancers
Aero2Max
A revolutionary smart training system for high-performance athletes
AgingSense
Wearing physiological sensors to monitor for exacerbations of heart failure
AltruMed
Axonova Medical
Proprietary technology platform allowing stretch growth of axon bundles for use as fully functional grafts to address peripheral and CNS neuropathies.
Calorint
Heat-based technology for wound healing
Cantius Therapeutics
$Cantius Therapeutics has a unique and well-placed strategy to treat cachexia and block nausea/emesis.
Carisma Therapeutics
$Cellular immunotherapy for solid tumors.
Carousel Therapeutics
$Carousel Therapeutics is developing a universal CAR-T targeting system for the treatment of relapse and refractory solid tumors.
Cartio
Developing CAR regulatory T cells to treat atherosclerosis and other cardiovascular diseases.
Cerespectus
Catheters using real time anatomic video feedback and fluoroscopic assistance for precise gene therapy delivery and treatment of other disorders of the central nervous system
Chip Diagnostics
$Lab-on-a-chip platform addressing the need for rapid, inexpensive, and highly sensitive diagnostics
Cogwear
$Affordable, mobile, comfortable, sustained, research-grade, brain state monitoring on the go
Cyloflux
Daimroc Imaging
Using Argentavue, a silver nanoparticle contrast agent for breast cancer imaging
Elaeis Therapeutics
EmboVent
EnaChip
$Developing magnetic materials, processes, and device designs that enable integration of magnetic components with silicon semiconductor devices
Enteropass
Developing novel enteric bypass solutions to change the paradigm of enterocutaneous fistula management
EpiVario
$Novel epigenetic therapeutics to treat complex psychiatric disorders
Evinacel
Exio
$Developing a diagnostic test to predict a patient’s responsiveness to cancer immunotherapy, with a focus on checkpoint inhibitor therapies.
FloBio
$Analyzes dynamic blood flow as a diagnostic technique in trauma, ER, and clinical settings
FluidiSpec
Fluorosurgical Biosciences
Forsagen
GastroVationX
Ghost Robotics
Building customizable robotic machines highly adept at perceiving tactile sensations
Hydropore
Hydropore is a clean technology start-up developing hydrogen fuel pellets for drones.
Hypknowledge
This app provides data-driven insights and recommendations to help people get their most, best sleep.
Hysplex
$Developing small molecule PARP inhibitors for the treatment of cancer and neurological disorders.
Infini – Fluidics
$Industry 4.0 in pharmaceutical and chemical manufacturing processes
Innervace
$Implantable tissue engineered brain pathways for neurodegenerative disorders.
Instanosis
$An innovative and broadly-applicable point-of-care platform to detect ultra-low concentrations of disease biomarkers.
Jericho Music Labs
A mobile platform for copyrighted music distribution
JT Me-Sh Diagnostics
Developing a novel point-of-care device to evaluate an individual’s exposure to radiation.
LignaMed
$Targeted therapeutics from flaxseed derivatives
Limbsalv
Advanced technology for limb salvage and reconstruction
Linnaeus
$Developing a G protein-coupled estrogen receptor (GPER) agonist with applicability across a range of cancers.
Liquid Biotech
Diagnostic blood test for sensitive detection of circulating tumor cells.
Mechano Therapeutics
$A therapeutic delivery platform using mechanically-activated microcapsule technology
MobileOptx
Applying portable electronic technology to advance the potential of endoscopic imagery
MyoArete
$MyoArete is developing newly identified utrophin upregulation therapies that treat all Duchenne Muscular Dystrophy patients.
Neuralert
$Robust wearable monitors to rapidly identify critically important neurological events such as stroke
Neurokappa Therapeutics
Treatments for cerebral vascular spasm using salvia divinosum
Neurostorative
Nia Therapeutics
$Developing responsive neurostimulation therapies for patients with dementia and other memory disorders.
Onocor
Catheter based retrieval systems designed to recovered malposition cardiovascular devices
OptCon
Software and sensor technology to enhance productivity, increase efficiency and automate processes for the construction, mining and infrastructure industries
Osciflex
Developing medical devices for the prevention of thrombosis
Osetomics
Diagnostic and prognostic tools for the treatment of acute musculoskeletal injuries, chronic orthopedic pathologies, and bone implant complications
Osteome Synthetica
Developing personalized synthetic bone substitutes that are precision printed.
Ostiio
$A novel approach to correct skeletal deformities and deficiencies using a fully implantable, magnetically-driven, bony distraction device
Paladai
Paradigm Analytics
Paradigm Surgical
$Prophylactic mesh augmentation systems for fascial reinforcement
Peroxitech
Novel therapeutic to prevent acute lung injury, the major cause of death with sepsis.
Pinpoint Therapeutics
$Developing novel autophagy inhibitor molecules for cancer treatment.
PolyAurum
Biodegradable gold nanoparticles to diagnose and treat diseases via enhanced x-ray attenuation
Prolifagen
Developing microRNA therapies to treat myocardial infarction, prevent remodeling, and regenerate tissue
Quantaras
$Advanced body-wide analysis of medical imagery for clinical and research purposes
Radix Therapeutics
Rafias
Recupero Robotics
Robotics for improved physical therapy
Ribovate Therapeutics
Ribovate is developing the next generation targeted mRNA-lipid nanoparticle therapeutic platform.
RightAir
Wearable device for respiratory assistance in COPD patients
Sapience Leadership
Consulting services on curricula, operational issues, and strategic planning
SchoolSims
Technology-enhanced immersive learning solutions to leadership development for educational and other organizations
Stage One Immunotherapeutics
TAIRIS
$Improving neurosurgery and neurosurgeons through anatomical pattern recognition assistance
TheraVal
Vasowatch
$Decision support technology for obstetrics to improve outcomes for all mothers
Vellum Biosciences
Non-invasive imaging diagnostic to differentiate cancer, inflammation, and infection
Veltion Therapeutics
Novel approaches for cancer treatment by targeting the Integrated Stress Response and its role in tumor as well as stroma adaptation to stress
Ventru
Versatilis Therapeutics
Vetigenics
Using novel phage-display techniques to develop reagents and therapeutics for veterinary medicine
Vital Start Health
Empowering clinicians and caregivers by giving them a digital platform to improve neonatal care
Vivodyne
Creating a groundbreaking 3D tissue culture pipeline and statistical inference engine to test drugs, biologics, and immunotherapies directly on ultra-realistic , bioengineered human tissues.
Apply now for the Spring 2022 Penn I-Corps cohort! The final deadline is March 1.