Penn inventors and researchers can choose to form startup companies leveraging their own expertise and partners or with direct support from Penn. PCI provides a number of programs that support startup formation through our PCI Ventures group, those resources can be found here.
Additionally, PCI works closely with Penn faculty to advise them on how to create a startup company as well as with new companies to license Penn technology.
Search our portfolio below, and click on each startup to learn more about their technologies, inventors, and whether they are looking for investors or new employees.
Development of vaccines and therapeutics for the treatment of infectious diseases and cancers
A revolutionary smart training system for high-performance athletes
Wearing physiological sensors to monitor for exacerbations of heart failure
Proprietary technology platform allowing stretch growth of axon bundles for use as fully functional grafts to address peripheral and CNS neuropathies.
Heat-based technology for wound healing
Cantius Therapeutics has a unique and well-placed strategy to treat cachexia and block nausea/emesis.
Cellular immunotherapy for solid tumors.
Carousel Therapeutics is developing a universal CAR-T targeting system for the treatment of relapse and refractory solid tumors.
Developing CAR regulatory T cells to treat atherosclerosis and other cardiovascular diseases.
Catheters using real time anatomic video feedback and fluoroscopic assistance for precise gene therapy delivery and treatment of other disorders of the central nervous system
Lab-on-a-chip platform addressing the need for rapid, inexpensive, and highly sensitive diagnostics
Affordable, mobile, comfortable, sustained, research-grade, brain state monitoring on the go
Using Argentavue, a silver nanoparticle contrast agent for breast cancer imaging
Developing magnetic materials, processes, and device designs that enable integration of magnetic components with silicon semiconductor devices
Developing novel enteric bypass solutions to change the paradigm of enterocutaneous fistula management
Novel epigenetic therapeutics to treat complex psychiatric disorders
Developing a diagnostic test to predict a patient’s responsiveness to cancer immunotherapy, with a focus on checkpoint inhibitor therapies.
Analyzes dynamic blood flow as a diagnostic technique in trauma, ER, and clinical settings
Building customizable robotic machines highly adept at perceiving tactile sensations
Hydropore is a clean technology start-up developing hydrogen fuel pellets for drones.
This app provides data-driven insights and recommendations to help people get their most, best sleep.
Developing small molecule PARP inhibitors for the treatment of cancer and neurological disorders.
Infini – Fluidics$
Industry 4.0 in pharmaceutical and chemical manufacturing processes
Implantable tissue engineered brain pathways for neurodegenerative disorders.
An innovative and broadly-applicable point-of-care platform to detect ultra-low concentrations of disease biomarkers.
Jericho Music Labs
A mobile platform for copyrighted music distribution
JT Me-Sh Diagnostics
Developing a novel point-of-care device to evaluate an individual’s exposure to radiation.
Targeted therapeutics from flaxseed derivatives
Advanced technology for limb salvage and reconstruction
Developing a G protein-coupled estrogen receptor (GPER) agonist with applicability across a range of cancers.
Diagnostic blood test for sensitive detection of circulating tumor cells.
A therapeutic delivery platform using mechanically-activated microcapsule technology
Applying portable electronic technology to advance the potential of endoscopic imagery
MyoArete is developing newly identified utrophin upregulation therapies that treat all Duchenne Muscular Dystrophy patients.
Robust wearable monitors to rapidly identify critically important neurological events such as stroke
Treatments for cerebral vascular spasm using salvia divinosum
Developing responsive neurostimulation therapies for patients with dementia and other memory disorders.
Catheter based retrieval systems designed to recovered malposition cardiovascular devices
Software and sensor technology to enhance productivity, increase efficiency and automate processes for the construction, mining and infrastructure industries
Developing medical devices for the prevention of thrombosis
Diagnostic and prognostic tools for the treatment of acute musculoskeletal injuries, chronic orthopedic pathologies, and bone implant complications
Developing personalized synthetic bone substitutes that are precision printed.
A novel approach to correct skeletal deformities and deficiencies using a fully implantable, magnetically-driven, bony distraction device
Prophylactic mesh augmentation systems for fascial reinforcement
Novel therapeutic to prevent acute lung injury, the major cause of death with sepsis.
Developing novel autophagy inhibitor molecules for cancer treatment.
Biodegradable gold nanoparticles to diagnose and treat diseases via enhanced x-ray attenuation
Developing microRNA therapies to treat myocardial infarction, prevent remodeling, and regenerate tissue
Advanced body-wide analysis of medical imagery for clinical and research purposes
Robotics for improved physical therapy
Ribovate is developing the next generation targeted mRNA-lipid nanoparticle therapeutic platform.
Wearable device for respiratory assistance in COPD patients
Consulting services on curricula, operational issues, and strategic planning
Technology-enhanced immersive learning solutions to leadership development for educational and other organizations
Improving neurosurgery and neurosurgeons through anatomical pattern recognition assistance
Non-invasive imaging diagnostic to differentiate cancer, inflammation, and infection
Novel approaches for cancer treatment by targeting the Integrated Stress Response and its role in tumor as well as stroma adaptation to stress
High performance steerable needle technology
Using novel phage-display techniques to develop reagents and therapeutics for veterinary medicine
Vital Start Health
Empowering clinicians and caregivers by giving them a digital platform to improve neonatal care
Creating a groundbreaking 3D tissue culture pipeline and statistical inference engine to test drugs, biologics, and immunotherapies directly on ultra-realistic , bioengineered human tissues.