In new research from the laboratories of Shelley Berger, PhD, the Daniel S. Och University Professor and Director of Penn’s Epigenetics Institute, and Katherine Alexander, PhD, currently an assistant professor at Cold Spring Harbor Laboratory have found that kidney tumors have two different patterns of cellular structures known as nuclear speckles. The research shows a potential correlation between speckle patterns and patient outcomes. These findings could pave the way for personalized treatments, matching patients to drugs based on their tumor’s speckle pattern. Researchers aim to further explore speckle patterns and their implications for clear cell renal cell carcinoma (ccRCC), the most common kidney cancer diagnosed in adults. Read the full Penn Medicine article here.
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