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Category: School of Medicine

The Center for Breakthrough Medicines and Penn partner in the manufacturing of gene therapies

Penn’s Innovation in Process Science combines with CBM manufacturing capability to develop large-scale gene therapy manufacturing capacity, testing, and analytics

Halting Progress and Happy Accidents: How mRNA vaccines were made

A New York Times feature on the history, research, challenges, and timeline to make the COVID-19 mRNA vaccines.

Moderna forms oncology collaboration with Carisma Therapeutics

Moderna will collaborate with Penn spinout Carisma Therapeutics to discover, develop and commercialize in-vivo engineered chimeric antigen receptor monocyte therapeutics for the treatment of cancer.

From foundational discoveries to profound impact

Without the mRNA technology foundation laid by Karikó and Weissman, the Pfizer/BioNTech and Moderna vaccines being deployed across the world would not exist.

Technology used in mRNA COVID vaccines offers hope for treatment of millions with heart disease, study suggests

Combining technologies that proved hugely success against cancer and in COVID-19 vaccines, researchers at Penn have shown they can effectively treat a leading cause of heart disease.

Vaccine-like mRNA injection can be used to make CAR T cells in the body

The researchers, whose work is published in Science, demonstrated the new approach with an mRNA preparation that reprograms T cells—a powerful type of immune cell—to attack heart fibroblast cells.

Katalin Karikó, PhD, featured on the cover of Newsweek as one of America’s Greatest Disruptors

She was described as being one of the 50 visionaries whose career-long actions have had far-reaching impact.

Scout Bio licenses new Penn technology to help develop gene therapies for pets

Scout Bio, a Philadelphia company developing gene therapies for animal health, has licensed a new kind of technology from the Penn’s gene therapy program.

Passage Bio further expands Gene Therapy research partnership with Penn

Passage Bio has exercised two additional options for potential new drug candidates under its research collaboration with Penn's gene therapy program.

A chewing gum that could reduce SARS-CoV-2 transmission

In experiments using saliva samples from COVID-19 patients, the gum, which contains the ACE2 protein, neutralized the virus, according to research led by School of Dental Medicine scientists.

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