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Category: School of Medicine

Carisma Therapeutics Announces First Patient Dosed in Phase 1 Clinical Trial of CT-0525, Appoints Eugene P. Kennedy as Chief Medical Officer  

Carisma announced the dosing of its first patient in its Phase 1 trial for CT-0525, an innovative CAR-Monocyte therapy targeting HER2-overexpressing solid tumors.

Verismo Therapeutics Achieves FDA Clearance for Phase I Trial of its CAR T Therapy 

Penn spinout Verismo Therapeutics has received FDA clearance for a Phase I trial of its CAR-T therapy, SynKIR-310.

iECURE Receives Three FDA Designations for its In Vivo Gene Insertion Program 

iEcure, a gene-editing company spun out of Penn and co-founded by Dr. Wilson, has received three special designations from the FDA for its new treatment, ECUR-506.

New Method Created for Improving the Resolution of Routine Medical Images

This novel method improves resolution of routine low resolution clinical images, saves MR scan time, and reduces radiation dosage levels for CT scanning.

Moderna Receives FDA Approval for RSV Vaccine Based on Penn Technology 

RSV is a highly contagious seasonal respiratory virus and a leading cause of lower respiratory tract infections and pneumonia.

Penn’s CAR-T Treatment Shrank Brain Tumors in Patients in Clinical Trial  

In a new early-stage clinical trial, a Penn-invented CAR-T treatment shrank brain tumors in seven patients with glioblastoma.

Capstan raises $175M Series B

Proceeds from the financing will be used to advance Capstan's lead in vivo chimeric antigen receptor T cell (CAR-T) candidate, CPTX2309, to early clinical proof-of-concept in autoimmune disorders.

iEcure Gains FDA approval to Conduct FirstGene Therapy Treatment  

Utilizing ARCUS, a gene editing tool developed by Precision BioSciences, the therapy aims to provide a lifelong fix for this disease, potentially benefiting thousands of individuals in the US alone.

Penn Researchers Discover New Technique to Form Human Artificial Chromosomes

Researchers at Penn led by Ben Black, PhD, the Eldridge Reeves Johnson Foundation Professor of Biochemistry and Biophysics, have found a new way to create synthetic chromosomes.

Philly Nonprofit Awarded $48 Million to Apply AI in Search for New Uses for Approved Drugs  

AI based on specific algorithms will scan tens of thousands of approved medications and rare diseases to find potential matches.

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