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Category: Startups

Penn Spinout Verismo Therapeutics Receives FDA Clearance of Investigational New Drug Application for SynKIR-110™, a KIR-CAR T Cell Immunotherapy Candidate

Verismo plans to begin enrolling patients in the first quarter of 2023 at the initial clinical site, the Hospital of the University of Pennsylvania.

Sesen Bio and Carisma Therapeutics Announce Merger Agreement

The combined company, which is expected to operate under the name Carisma Therapeutics Inc., will focus on advancing Carisma’s proprietary cell therapy platform.

Penn spinout Capstan Therapeutics Launches with Goal of Incorporating mRNA into CAR-T Cell Therapy

This new approach to CAR-T therapy will involve mRNA therapy that directs cells in the body to make proteins to prevent or fight disease.

B.PHL Innovation Festival: PCIV Startup VasoWatch LLC and PCI I-Corps Participant Viora Health Featured

The event, which served as a gathering place for local and global creatives, entrepreneurs, leaders, students, and industry changemakers, featured some incredible Penn startups.

Penn Inventors Recognized as Philadelphia Business Journal’s Inno Under 25 Honorees

Their innovative work was recognized by the Philadelphia Business Journal's PHL Inno initiative, which awards people 25 years and younger who are making an impact in the area’s startup ecosystem.

Penn Spinout Interius BioTherapeutics Is Developing Tools to Perform Cell and Gene Engineering Directly in the Human Body

The hope is that this new technology could simplify the process of CAR-T cell therapy and make gene therapy widely available as a one-time injection to a much larger number of patients.

PCI Startup SchoolSims Named One of the 100 Fastest Growing Companies in the Philadelphia Region by Philadelphia100® Forum

SchoolSims is an education company that offers technology-enhanced immersive learning solutions to leadership development for educational and other organizations.

Penn Spinout Verismo Therapeutics Announces Submission of Investigational New Drug Application to the FDA for KIR-CAR T-cell Immunotherapy Candidate

Pending regulatory approval, Verismo plans to use the drug in patients with mesothelin-expressing ovarian cancer, mesothelioma and cholangiocarcinoma.

Penn Gene-Editing Spinout iEcure Receives Rare Pediatric Disease Designation from FDA for Lead Drug Candidate

iEcure is developing the new drug candidate, GTP-506, as a treatment for a rare genetic condition caused by a genetic defect in a liver enzyme responsible for detoxification of ammonia.

Philadelphia Innovation Hub Experiences Explosive Growth in Manufacturing, Research and Talent

Philadelphia's innovation hub has seen explosive growth over the past several years, with significant expansions in manufacturing and research space for multiple companies.

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