Penn Medicine Researchers Use AI to Uncover Potential Antibiotic Compounds

A Penn Medicine research team led by César de la Fuente, PhD, Presidential Associate Professor in Psychiatry, Microbiology, Chemistry, Chemical and Biomolecular Engineering, and Bioengineering has used AI to analyze the genomes of tens of thousands of bacteria and other primitive organisms, uncovering nearly one million potential new antibiotic compounds. This groundbreaking study, published in Cell, represents the largest antibiotic discovery effort in recent years, significantly accelerating the process of identifying candidate molecules.  
 
“AI in antibiotic discovery is now a reality and has significantly accelerated our ability to discover new candidate drugs,” said Dr. de la Fuente, as per the Penn Bioengineering Blog.  “What once took years can now be achieved in hours using computers.” Read more here and here.

PCI is actively seeking partners and investors for further development of this promising technology. For more information, contact Gangotri Dey, PhD, Licensing Officer, PCI. 

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