AbbVie Inc., headquartered in Lake Bluff, Illinois, has entered into two separate multi-year Sponsored Research Agreements with the lab of Gary Molander, PhD, Professor of Chemistry in the School of Arts & Sciences.
The Molander lab, with their expertise in photoredox chemistry, is initially investigating the synthesis of complex, strained, bicyclic systems. In the second project, the group will apply these building blocks as cross-coupling partners with various DNA-conjugated substrates.
The goal of this work is focused on the development of DNA-compatible methods to install C(sp3)-rich chemical matter, available for DNA-encoded library production. These libraries are used as vital tools in the academic research and drug development industry to simultaneously screen billions of potentially bio-active compounds.