These obese mice lost weight by ‘sweating’ their fat, Penn team finds

In search of better treatments for type 2 diabetes and other consequences of obesity, Taku Kambayashi has long wondered if he could harness a bodily function that most people think about in a very different context: the immune system. There was evidence to suggest this approach might work, as certain types of immune cells were known to play a role in metabolism.

But when he and University of Pennsylvania colleagues stimulated these cells in a series of experiments on obese mice, they got a surprise. Not only did the animals become healthier in terms of their blood-glucose levels and other metabolic “markers,” they also lost dramatic amounts of weight.

Read More in the Philadelphia Inquirer

Taku Kambayashi
Taku Kambayashi
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