Looking to solve the solid tumor puzzle box, Carisma aims to take ‘CAR-M’ groundbreaker into early-stage trial

In an effort to crack the code of hard-to-treat solid tumors, biopharma has tried numerous pathways to effectively target those masses without damaging healthy tissues. Philly’s Carisma Therapeutics thinks it has a winner with its macrophage cell-based “CAR-M” candidates, and now it’s taking a new flush of investor cash to try one in the clinic.

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