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Category: Startups

Cabaletta Bio Receives Another FDA Clearance for IND application of CABA-201

The company plans to initiate a Phase 1/2 clinical trial of CABA-201 in two cohorts of patients with generalized myasthenia gravis (gMG).

Heirloom Opens First Commercial Carbon Capture Plant in the U.S.

Heirloom uses a process called direct air capture to remove greenhouse gases from the atmosphere.

Vetigenics’ Treats its First Canine Cancer Patient

Vetigenics announced that the first canine patient has received his first dose of Vetigenics' fully canine anti-CTLA4 monoclonal antibody (VGS-001) for oral melanoma.

IND Clearance Achieved by Cabaletta Bio

Cabaletta Bio received FDA clearance for their fourth Investigational New Drug application of CABA-201, their CAR T cell investigational therapy, to treat patients with generalized myasthenia gravis.

Penn spinout Interius Biotherapeutics raises another $21.5M

Co-founded by Saar Gill, MD, PhD, Interius is developing a new platform for cell-specific gene delivery in patients.

FloBio Receives the FDA’s Breakthrough Device Designation for its Bleeding Risk Diagnostic Test

FloBio's test determines blood clotting status and identifies whether a patient is on popular blood thinners called Direct Oral Anticoagulants (DOACs).

Opus Genetics Announces First Patient Dosed in Phase 1/2 Trial of Gene Therapy OPGx-LCA5 in Patients with Rare Inherited Retinal Disease LCA5 

Penn spinout Opus Genetics announced that the first patient has been dosed in its Phase 1/2, first-in-human clinical trial of OPGx-LCA5.

Penn Spinout Heirloom Technologies and Microsoft Sign One of the Largest Permanent CO2 Removal Deals To-Date 

Microsoft signed a long term contract to purchase up to 315,000 metric tons of CO2 removal over a multi-year period from Penn spinout Heirloom Carbon Technologies.

BlueWhale Bio, a New Cell Therapy Production Company, Emerges from Stealth Mode 

In September 2023, Penn spinout BlueWhale Bio surfaced with a mission to overhaul cell therapy production.

Exyn Technologies Closes on Series B Funding

Exyn has a mission to deliver world-class autonomous robots to data-hungry industries that include mining, logistics and construction. 

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